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Article

ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions.

Human molecular genetics - 1 Apr 2015

Levy Michael A, Kernohan Kristin D, Jiang Yan, Bérubé Nathalie G

Abstract excerpt

ATRX is a chromatin remodeling protein involved in deposition of the histone variant H3.3 at telomeres and pericentromeric heterochromatin. It also influences the expression level of specific genes; however, deposition of H3.3 at transcribed genes is currently thought to occur independently of ATRX. We focused on a set of genes, including the autism susceptibility gene Neuroligin 4 (Nlgn4), that exhibit decreased...

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PMID: 25452430
DOI: 10.1093/hmg/ddu596

Genes

ATRX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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