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Article

CaMKII isoforms differ in their specific requirements for regulation by nitric oxide.

FEBS letters - 20 Dec 2014

Coultrap Steven J, Zaegel Vincent, Bayer K Ulrich

Abstract excerpt

The Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) mediates physiological and pathological functions by its Ca(2+)-independent autonomous activity. Two novel mechanisms for generating CaMKII autonomy include oxidation and S-nitrosylation, the latter requiring both Cys280 and Cys289 amino acid residues in the brain-specific isoform CaMKIIα. Even though the other CaMKII isoforms have a different amino acid...

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Identifiers

PMID: 25447522
DOI: 10.1016/j.febslet.2014.10.039
PMCID: PMC4312479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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