Article
Crosstalk between JNK and NF-κB signaling pathways via HSP27 phosphorylation in HepG2 cells.
Biochemical and biophysical research communications - 2 Jan 2015
Ruan Jie, Qi Zhilin, Shen Lei, Jiang Yi, Xu Yimiao, Lan Lei, Luo Lan, Yin Zhimin
Abstract excerpt
The crosstalk of intracellular signaling pathways is extremely complex. Previous studies have shown that there is a potential crosstalk between MAPKs and NF-κB signaling pathways. It has been reported that JNK regulates cell survival under some conditions. But the molecular mechanism through which JNK regulates cell survival is still unclear. In the present study, we hypothesized that there was a crosstalk...
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