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Article

The function of heat shock protein 27 in interleukin-1 signalling

2009-01-01

Abstract excerpt

The p38 mitogen activated protein kinase (MAPK) pathway enhances the expression of proinflammatory response genes, including cyclooxgenase (COX)-2 and interleukin (IL)-6 in response to stimuli including IL-1. Heat shock protein 27 (HSP27) is a major protein phosphorylated by MAPK activated protein kinase 2 (MK2), a downstream kinase of p38 MAPK. However, the role of HSP27 in inflammation is unclear. Previous work...

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Literature Corpus work
68ba7d2d-fe82-5d6b-95e7-6227ceea70e1
DOI
10.25560/6159
Open publication

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