Article
Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
Circulation research - 30 Apr 2010
Ota Asuka, Zhang Jun, Ping Peipei, Han Jiahuai, Wang Yibin
Abstract excerpt
RATIONALE: p38 is an important stress activated protein kinase involved in gene regulation, proliferation, differentiation, and cell death regulation in heart. p38 kinase activity can be induced through canonical pathway via upstream kinases or by noncanonical autophosphorylation. The intracellul...
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