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Article

Inhibition of Daxx-mediated apoptosis by heat shock protein 27.

Molecular and cellular biology - 1 Oct 2000

Charette S J, Lavoie J N, Lambert H, Landry J

Abstract excerpt

Heat shock protein 27 (HSP27) confers cellular protection against a variety of cytotoxic stresses and also against physiological stresses associated with growth arrest or receptor-mediated apoptosis. Phosphorylation modulates the activity of HSP27 by causing a major change in the supramolecular organization of the protein, which shifts from oligomers to dimers. Here we show that phosphorylated dimers of HSP27...

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Identifiers

PMID: 11003656
DOI: 10.1128/MCB.20.20.7602-7612.2000
PMCID: PMC86317

Genes

FADD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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