Article
Role of Drosophila calcium channel cacophony in dopaminergic neurodegeneration and neuroprotection.
Neuroscience letters - 1 Jan 2015
Wiemerslage Lyle, Lee Daewoo
Abstract excerpt
One of the most important questions in Parkinson's disease (PD) regards the selective vulnerability of a specific population of dopaminergic (DA) neurons. Recent reports identify Ca(2+) channel as a potential source of this vulnerability. This work uses a Drosophila primary neuronal cell culture system as an in vitro PD model to explore the role of Ca(2+) homeostasis in DA neurodegeneration and protection. Our...
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