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Article

Ileal neuroendocrine tumors show elevated activation of mammalian target of rapamycin complex.

The Journal of surgical research - 1 Apr 2015

Geis Christian, Fendrich Volker, Rexin Peter, Di Fazio Pietro, Bartsch Detlef K, Ocker Matthias, Quint Karl, Heverhagen Anna E

Abstract excerpt

BACKGROUND: Neuroendocrine tumors (NETs) of the ileum are sporadic tumors derived from submucosal gastrointestinal stem cells. They often show clinical symptoms only after hepatic metastasation when curative therapy is limited or impossible. In this study, we analyzed the expression of the candidate genes mammalian target of rapamycin (mTOR), alpha thalassemia/mental retardation syndrome X-linked (ATRX), and...

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Source

Identifiers

PMID: 25439321
DOI: 10.1016/j.jss.2014.10.052

Genes

ATRX
DAXX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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