Article
Profiling mTOR pathway in neuroendocrine tumors.
Targeted oncology - 1 Sept 2012
Cingarlini S, Bonomi M, Corbo V, Scarpa A, Tortora G
Abstract excerpt
The serine/threonine kinase mammalian target of rapamycin (mTOR) plays a central role in regulating critical cellular processes such as growth, proliferation, and protein synthesis. The study of cancer predisposing syndromes within which neuroendocrine tumors (NETs) may arise has furnished clues on the involvement of mTOR pathway in sporadic diseases so far. Recent comprehensive analyses have definitely shown...
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