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Article

DNA Consensus Sequence Motif for Binding Response Regulator PhoP, a Virulence Regulator of <i>Mycobacterium tuberculosis</i>

1 Dec 2014

Abstract excerpt

Tuberculosis has reemerged as a serious threat to human health because of the increasing prevalence of drug-resistant strains and synergetic infection with HIV, prompting an urgent need for new and more efficient treatments. The PhoP-PhoR two-component system of Mycobacterium tuberculosis plays an important role in the virulence of the pathogen and thus represents a potential drug target. To study the mechanism...

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PMID: 25434965
DOI: 10.1021/bi501019u

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DNA Consensus Sequence Motif for Binding Response Regulator PhoP, a Virulence Regulator of <i>Mycobacterium tuberculosis</i>PMID 25434965Read ↗

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