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Article

An invasive and low virulent Edwardsiella tarda esrB mutant promising as live attenuated vaccine in aquaculture.

Applied microbiology and biotechnology - 1 Feb 2015

Yang Weizheng, Wang Lixia, Zhang Lingzhi, Qu Jiangbo, Wang Qiyao, Zhang Yuanxing

Abstract excerpt

Edwardsiella tarda is a leading fish pathogen haunting worldwide aquaculture industry. In E. tarda, two-component system EsrA-EsrB positively regulates type III and VI secretion systems (T3SS and T6SS) and negatively regulates hemolysin EthA, which has been demonstrated to be essential for the invasion processes in fish. In order to develop a live attenuated vaccine (LAV) with high invasiveness to be practically...

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Identifiers

PMID: 25431010
DOI: 10.1007/s00253-014-6214-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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