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Article

Functional genomics approach to the identification of virulence genes involved in Edwardsiella tarda pathogenesis.

Infection and immunity - 1 Mar 2003

Srinivasa Rao Putanae S, Lim Tit Meng, Leung Ka Yin

Abstract excerpt

Edwardsiella tarda is an important cause of hemorrhagic septicemia in fish and also of gastro- and extraintestinal infections in humans. Here, we report the identification of 14 virulence genes of pathogenic E. tarda that are essential for disseminated infection, via a genome-wide analysis. We screened 490 alkaline phosphatase fusion mutants from a library of 450,000 TnphoA transconjugants derived from strain...

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Identifiers

PMID: 12595451
DOI: 10.1128/IAI.71.3.1343-1351.2003
PMCID: PMC148833

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