Article
Type III secretion system genes of Edwardsiella tarda associated with intracellular replication and virulence in zebrafish.
Diseases of aquatic organisms - 21 Aug 2014
Okuda Jun, Takeuchi Yusuke, Nakai Toshihiro
Abstract excerpt
The Type III secretion system (T3SS) is essential for intracellular replication of Edwardsiella tarda in phagocytes of fish and mammals. Two possible effector candidate genes (eseE and eseG) and 7 hypothetical genes (esaB, escC, orf13, orf19, orf26, orf29, and orf30) located in the T3SS gene cluster were inactivated by an allelic exchange method, and we found that E. tarda strains carrying insertion mutations in...
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