Article
Phenotypic characterization, virulence, and immunogenicity of Edwardsiella tarda LSE40 aroA mutant.
Applied microbiology and biotechnology - 1 Jul 2013
Mo Zhao-Lan, Li Jie, Li Gui-Yang, Xiao Peng
Abstract excerpt
Bacterial aro mutants are frequently used as live attenuated vaccines for domestic animals. In this study, we characterized Edwardsiella tarda strain LSE40 with a deletion in the aroA gene. In addition to autotrophy, the aroA mutant appeared to have delayed cell division and reductions in its swarming motility, biofilm formation, and production of translocator proteins in the type III secretory system. The mutant...
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