Article
Edwardsiella tarda mutant disrupted in type III secretion system and chorismic acid synthesis and cured of a plasmid as a live attenuated vaccine in turbot.
Fish & shellfish immunology - 1 Sept 2013
Xiao Jingfan, Chen Tao, Liu Bing, Yang Weizheng, Wang Qiyao, Qu Jiangbo, Zhang Yuanxing
Abstract excerpt
Edwardsiella tarda is an intractable Gram-negative pathogen in many fish species to cause edwardsiellosis. Its infection leads to extensive losses in a diverse array of commercially important fish. The type III secretion system (T3SS) has been considered as one of the major virulence factors and plays important roles in its intracellular lifestyle. In this study, an E. tarda EIB202 mutant WED with deletions in...
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