Article
Effect of diversity and missing data on genetic assignment with RAD-Seq markers.
BMC research notes - 25 Nov 2014
Chattopadhyay Balaji, Garg Kritika M, Ramakrishnan Uma
Abstract excerpt
Reduced representation libraries are being used as a preferred source of markers to address population genetic questions. However, libraries of RAD-Seq variants often suffer from significant percentage of missing data. In addition, algorithms used to mine SNPs from the raw data may also underscore biological variation. We investigate the effect of biological diversity in mining SNPs from the program STACKS and...
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