Article
Allele identification in assembled genomic sequence datasets.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Dlugosch Katrina M, Bonin Aurélie
Abstract excerpt
Allelic variation within species provides fundamental insights into the evolution and ecology of organisms, and information about this variation is becoming increasingly available in sequence datasets of multiple and/or outbred individuals. Unfortunately, identifying true allelic variants poses a number of challenges, given the presence of both sequencing errors and alleles from other closely related loci. We...
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