Sensitizing effect of early adversity on depressive reactions to later proximal stress: Moderation by polymorphisms in serotonin transporter and corticotropin releasing hormone receptor genes in a 20-year longitudinal study

doi:10.1017/s0954579414000996

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Sensitizing effect of early adversity on depressive reactions to later proximal stress: Moderation by polymorphisms in serotonin transporter and corticotropin releasing hormone receptor genes in a 20-year longitudinal study

1 Nov 2014

Abstract excerpt

Previous research supports gene-environment interactions for polymorphisms in the corticotropin hormone receptor 1 gene (CRHR1) and the serotonin transporter gene linked polymorphic region (5-HTTLPR) in predicting depression, but it has rarely considered genetic influences on stress sensitization processes, whereby early adversities (EA) increase depressive reactivity to proximal stressors later in life. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child and Adolescent Psychosocial and Emotional Development
Share to Maternal Mental Health During Pregnancy and Postpartum
Share to Stress Responses and Cortisol

Source

Open in PubMed

Identifiers

PMID: 25422958
DOI: 10.1017/s0954579414000996

Provenance

PubMed metadata and Literature Corpus relationships.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics