Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

β-Catenin Signaling Evokes Hair Follicle Senescence by Accelerating the Differentiation of Hair Follicle Mesenchymal Progenitors

4 Apr 2022

Abstract excerpt

Rationale: β-catenin signaling controls multiple fibroblast subsets, with its overactivity promoting the differentiation of hair follicle dermal stem cells (hfDSCs) and the hyperactivation of interfollicular fibroblasts. Understanding the concept of hfDSC activation and modulation offers hope towards the therapeutic armamentarium in dermatology and related comorbidities, as well as their potential applications in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hair Growth and Disorders
Share to Skin and Cellular Biology Research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35478971
DOI: 10.3389/fcell.2022.839519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

β-Catenin Signaling Evokes Hair Follicle Senescence by Accelerating the Differentiation of Hair Follicle Mesenchymal ProgenitorsPMID 35478971Read ↗

Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis.Semantic proximity Read ↗

Signaling pathways in hair agingSemantic proximity Read ↗

Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapiesSemantic proximity Read ↗

Targeting IGF1 ‐Induced Cellular Senescence to Rejuvenate Hair Follicle AgingSemantic proximity Read ↗

Dermal papilla cell number specifies hair size, shape and cycling and its reduction causes follicular declineSemantic proximity Read ↗

Escape of hair follicle stem cells causes stem cell exhaustion during agingSemantic proximity Read ↗

Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challengesSemantic proximity Read ↗

Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of AlopeciaSemantic proximity Read ↗

MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.Semantic proximity Read ↗

Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound HealingSemantic proximity Read ↗

Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem CellsSemantic proximity Read ↗

Disruption of Smad4 in mouse epidermis leads to depletion of follicle stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.