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Wnt Signaling in the Breast: From Development to Disease

18 May 2022

Abstract excerpt

The Wnt cascade is a primordial developmental signaling pathway that plays a myriad of essential functions throughout development and adult homeostasis in virtually all animal species. Aberrant Wnt activity is implicated in embryonic and tissue morphogenesis defects, and several diseases, most notably cancer. The role of Wnt signaling in mammary gland development and breast cancer initiation, maintenance, and...

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PMID: 35663403
DOI: 10.3389/fcell.2022.884467

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