Article
Comprehensive characterization of the genomic alterations in human gastric cancer.
International journal of cancer - 1 Jul 2015
Cui Juan, Yin Yanbin, Ma Qin, Wang Guoqing, Olman Victor, Zhang Yu, Chou Wen-Chi, Hong Celine S, Zhang Chi, Cao Sha, Mao Xizeng, Li Ying, Qin Steve, Zhao Shaying, Jiang Jing, Hastings Phil, Li Fan, Xu Ying
Abstract excerpt
Gastric cancer is one of the most prevalent and aggressive cancers worldwide, and its molecular mechanism remains largely elusive. Here we report the genomic landscape in primary gastric adenocarcinoma of human, based on the complete genome sequences of five pairs of cancer and matching normal samples. In total, 103,464 somatic point mutations, including 407 nonsynonymous ones, were identified and the most...
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