Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis B Virus HBx Protein Interactions with the Ubiquitin Proteasome System

24 Nov 2014

Abstract excerpt

The hepatitis B virus (HBV) causes acute and chronic hepatitis, and the latter is a major risk factor for the development of hepatocellular carcinoma (HCC). HBV encodes a 17-kDa regulatory protein, HBx, which is required for virus replication. Although the precise contribution(s) of HBx to virus replication is unknown, many viruses target cellular pathways to create an environment favorable for virus replication....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Hepatitis B Virus Studies
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25421893
DOI: 10.3390/v6114683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis B Virus HBx Protein Interactions with the Ubiquitin Proteasome SystemPMID 25421893Read ↗

Hepatitis B Viral Protein HBx and the Molecular Mechanisms Modulating the Hallmarks of Hepatocellular Carcinoma: A Comprehensive ReviewSemantic proximity Read ↗

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase ComplexSemantic proximity Read ↗

RNA Helicase DDX17 Inhibits Hepatitis B Virus Replication by Blocking Viral Pregenomic RNA EncapsidationSemantic proximity Read ↗

Mechanism of inhibiting type I interferon induction by hepatitis B virus X proteinSemantic proximity Read ↗

Hepatitis B virus-induced hepatocellular carcinoma: The role of the virus x proteinSemantic proximity Read ↗

Hepatitis B virus X protein modulates upregulation of DHX9 to promote viral DNA replicationSemantic proximity Read ↗

The oncogenic role of hepatitis B virus X gene in hepatocarcinogenesis: recent updatesSemantic proximity Read ↗

Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx proteinSemantic proximity Read ↗

The Ubiquitin System and Kaposi’s Sarcoma-Associated HerpesvirusSemantic proximity Read ↗

Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex.Semantic proximity Read ↗

The Role of the Host Ubiquitin System in Promoting Replication of Emergent VirusesSemantic proximity Read ↗

Hepatitis B virus X gene and hepatocarcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.