Article
Turnover of hepatitis B virus X protein is regulated by damaged DNA-binding complex.
Journal of virology - 1 Jul 2002
Bergametti Françoise, Sitterlin Delphine, Transy Catherine
Abstract excerpt
Mammalian hepatitis B viruses encode an essential regulatory protein, termed X, which may also be implicated in liver cancer development associated with chronic infection. X protein, also referred to as HBx in human virus and WHx in woodchuck virus, has been reported to bind to a number of cellular proteins, including the DDB1 subunit of the damaged DNA-binding (DDB) complex. Our previous work provided genetic...
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