Article
MSCs with ACE II gene affect apoptosis pathway of acute lung injury induced by bleomycin.
Experimental lung research - 1 Feb 2015
Zhang Xiaomiao, Gao Fengying, Li Qian, Dong Zhixia, Sun Bo, Hou Lili, Li Zhuozhe, Liu Zhenwei
Abstract excerpt
PURPOSE: The aim of this study was to evaluate the effect and related mechanisms of Mesenchymal stem cells (MSCs) and Angiotensin converting enzyme II (ACE II) on acute lung injury (ALI). METHODS: MSCs were separated from umbilical cord cells, and the changes of phenotype before and after ACE II silence were observed using Flow Cytometer. ALI model was induced by 10 mg/mL bleomycin in 60 Balb/c mice, and the rest...
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