Article
Mesenchymal stem cell-based angiotensin-converting enzyme 2 in treatment of acute lung injury rat induced by bleomycin.
Experimental lung research - 1 Oct 2014
Gao Fengying, Li Qian, Hou Lili, Li Zhuozhe, Min Fang, Liu Zhenwei
Abstract excerpt
BACKGROUND: Acute lung injury (ALI) is a high incidence disease with no effective therapeutic method (mortality rate > 40%). The aim of this study was to find a new and effective therapeutic method for ALI. METHODS: After the isolation of human umbilical cord mesenchymal stem cells (HUMSCs) from cesarean fetus, we transfected the HUMSCs with Lenti-ACE2 (angiotensin-converting enzyme 2) viral particles. Then we...
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