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Angiotensin II induces apoptosis in human induced pluripotent stem cell-derived cardiomyocytes

2020-03-20

Abstract excerpt

<h4>Background</h4> The renin-angiotensin system (RAS) functions fundamentally to regulate the pathological process of cardiovascular diseases, such as heart failure and hypertension. As the major effector in RAS, angiotensin II activates angiotensin II receptors to initiate the downstream pathways, which lead to the phenotypes including apoptosis, hypertrophy, and cardiac remodeling. Human induced pluripotent st...

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Literature Corpus work
cb17c60b-2ba2-5520-b3c6-251ef9c54401
DOI
10.1101/2020.03.19.998344
Open publication

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