Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic effect of human umbilical cord mesenchymal stem cells modified by angiotensin-converting enzyme 2 gene on bleomycin-induced lung fibrosis injury.

Molecular medicine reports - 1 Apr 2015

Min Fang, Gao Fengying, Li Qian, Liu Zhenwei

Abstract excerpt

The aim of the present study was to evaluate the therapeutic effects of human umbilical cord mesenchymal stem cells (uMSCs) in the presence of angiotensin‑converting enzyme 2 gene (ACE2; ACE2‑uMSCs) on bleomycin (BLM)‑induced lung injury and pulmonary fibrosis in mice. A total of 100 male C57BL/6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to Bleomycin
Share to Fetal Blood

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lentivirus

Share to Lung Injury

Share to Matrix Metalloproteinases

Share to Mesenchymal Stem Cell Transplantation

Share to Tissue Inhibitor of Metalloproteinases

Source

Open in PubMed Open full text

Identifiers

PMID: 25435005
DOI: 10.3892/mmr.2014.3025
PMCID: PMC4337478

Genes

ACE2
BLM
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25435005-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic effect of human umbilical cord mesenchymal stem cells modified by angiotensin-converting enzyme 2 gene on bleomycin-induced lung fibrosis injury.PMID 25435005Read ↗

Mesenchymal stem cell-based angiotensin-converting enzyme 2 in treatment of acute lung injury rat induced by bleomycin.Semantic proximity Read ↗

MSCs with ACE II gene affect apoptosis pathway of acute lung injury induced by bleomycin.Semantic proximity Read ↗

Therapies for bleomycin induced lung fibrosis through regulation of TGF‐β1 induced collagen gene expressionSemantic proximity Read ↗

Meleagrin Isolated from the Red Sea Fungus Penicillium chrysogenum Protects against Bleomycin-Induced Pulmonary Fibrosis in MiceSemantic proximity Read ↗

Transplantation of human embryonic stem cell-derived alveolar epithelial type II cells abrogates acute lung injury in mice.Semantic proximity Read ↗

CYP2J2 and EETs Protect Against Pulmonary Hypertension with Lung Ischemia-Reperfusion Injury In Vivo and In VitroSemantic proximity Read ↗

Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial CellsSemantic proximity Read ↗

Umbilical cord mesenchymal stem cell alleviates asthma via Nrf2/HO-1/NF-κB signaling pathwaySemantic proximity Read ↗

Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary FibrosisSemantic proximity Read ↗

Olmesartan Attenuates Single-Lung Ventilation Induced Lung Injury via Regulating Pulmonary MicrobiotaSemantic proximity Read ↗

The Effects of Inhaling Hydrogen Gas on Macrophage Differentiation, Fibrosis and Lung Function in Mice with Bleomycin-induced Lung InjurySemantic proximity Read ↗

Therapeutic Use of Stem Cell Transplantation for Cell Replacement or Cytoprotective Effect of Microvesicle Released from Mesenchymal Stem CellSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.