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Gene Engineered Mesenchymal Stem Cells: Greater Transgene Expression and Efficacy With Minicircle Vs. Plasmid DNA Vectors in a Mouse Model of Acute Lung Injury

2020-10-21

Abstract excerpt

<title>Abstract</title> <p>Background: Acute lung injury (ALI), and in its severe form the Acute respiratory distress syndrome (ARDS), results in increased pulmonary vascular inflammation and permeability, and is a major cause of mortality in many critically ill patients. Although cell-based therapies have shown promise in experimental ALI, strategies are needed to enhance potency of mesenchymal stem cells (MSC)...

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Literature Corpus work
f01cccc3-6815-5612-9c48-fe9a8afddee4
DOI
10.21203/rs.3.rs-94157/v1
Open publication

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Gene Engineered Mesenchymal Stem Cells:&nbsp;Greater Transgene Expression and Efficacy With Minicircle Vs. Plasmid DNA&nbsp;Vectors in a Mouse Model of Acute Lung InjuryDOI 10.21203/rs.3.rs-94157/v1
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