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Article

Role of C/EBP homologous protein in retinal ganglion cell death after ischemia/reperfusion injury.

Investigative ophthalmology & visual science - 20 Nov 2014

Nashine Sonali, Liu Yang, Kim Byung-Jin, Clark Abbot F, Pang Iok-Hou

Abstract excerpt

PURPOSE: To investigate the role of C/EBP homologous protein (CHOP), a proapoptotic protein, and the unfolded protein response (UPR) marker that is involved in endoplasmic reticulum (ER) stress-mediated apoptosis in mouse retinal ganglion cell (RGC) death following ischemia/reperfusion (I/R) injury. METHODS: Retinal I/R injury was induced in adult C57BL/6J wild-type (WT) and CHOP knockout (Chop(-/-)) mice by...

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Source

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Identifiers

PMID: 25414185
DOI: 10.1167/iovs.14-15447
PMCID: PMC4544595

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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