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Article

Decreased retinal neuronal cell death in caspase-1 knockout mice.

Japanese journal of ophthalmology - 1 Jan 2000

Arai Jun, Katai Naomichi, Kuida Keisuke, Kikuchi Takanobu, Yoshimura Nagahisa

Abstract excerpt

PURPOSE: To determine whether apoptosis of retinal neurons induced by excessive light exposure and ischemia-reperfusion injury is altered in caspase-1 knockout mice. METHODS: Eight- to 10-week-old caspase-1 knockout mice (Casp1-/-) and wild-type (WT) mice (C57BL/6) were exposed to diffuse, cool, white fluorescent light of 25,000 lux for 2 h. Other mice were subjected to retinal ischemia by increasing the...

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Identifiers

PMID: 17013693
DOI: 10.1007/s10384-006-0352-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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