Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caspases in retinal ganglion cell death and axon regeneration

3 Jul 2017

Abstract excerpt

Retinal ganglion cells (RGC) are terminally differentiated CNS neurons that possess limited endogenous regenerative capacity after injury and thus RGC death causes permanent visual loss. RGC die by caspase-dependent mechanisms, including apoptosis, during development, after ocular injury and in progressive degenerative diseases of the eye and optic nerve, such as glaucoma, anterior ischemic optic neuropathy,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Inflammasome and immune disorders
Share to Ocular Diseases and Behçet’s Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29675270
DOI: 10.1038/cddiscovery.2017.32

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caspases in retinal ganglion cell death and axon regenerationPMID 29675270Read ↗

Neuroprotective Strategies for the Treatment of Inherited Photoreceptor DegenerationSemantic proximity Read ↗

Mechanisms of cell death in neurodegenerative and retinal diseasesSemantic proximity Read ↗

Role of Interleukin-21 in retinal ischemia-reperfusion injury: Unveiling the impact on retinal ganglion cell apoptosisSemantic proximity Read ↗

Retinal Ganglion Cell Death in Glaucoma: Advances and CaveatsSemantic proximity Read ↗

Targeting Necroptosis: A Novel Therapeutic Option for Retinal Degenerative DiseasesSemantic proximity Read ↗

Inhibiting multiple forms of cell death optimizes ganglion cells survival after retinal ischemia reperfusion injurySemantic proximity Read ↗

Retinal Inflammation, Cell Death and Inherited Retinal DystrophiesSemantic proximity Read ↗

The molecular mechanisms underlying retinal ganglion cell apoptosis and optic nerve regeneration in glaucoma (Review)Semantic proximity Read ↗

Programmed Non-Apoptotic Cell Death in Hereditary Retinal Degeneration: Crosstalk between cGMP-Dependent Pathways and PARthanatos?Semantic proximity Read ↗

Signalling pathways and cell death mechanisms in glaucoma: Insights into the molecular pathophysiologySemantic proximity Read ↗

RIPK3 suppresses photoreceptor degeneration in a Stargardt disease mouse modelSemantic proximity Read ↗

Apoptosis in ocular disease: a molecular overviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.