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Article

Remnant cholesterol, low-density lipoprotein cholesterol, and blood pressure as mediators from obesity to ischemic heart disease.

Circulation research - 13 Feb 2015

Varbo Anette, Benn Marianne, Smith George Davey, Timpson Nicholas J, Tybjaerg-Hansen Anne, Nordestgaard Børge G

Abstract excerpt

RATIONALE: Obesity leads to increased ischemic heart disease (IHD) risk, but the risk is thought to be mediated through intermediate variables and may not be caused by increased weight per se. OBJECTIVE: To test the hypothesis that the increased IHD risk because of obesity is mediated through lipoproteins, blood pressure, glucose, and C-reactive protein. METHODS AND RESULTS: Approximately 90 000 participants from...

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Source

Identifiers

PMID: 25411050
DOI: 10.1161/CIRCRESAHA.116.304846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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