Article
Quantifying Triglyceride-Rich Lipoprotein Atherogenicity, Associations With Inflammation, and Implications for Risk Assessment Using Non-HDL Cholesterol.
Journal of the American College of Cardiology - 1 Oct 2024
Björnson Elias, Adiels Martin, Gummesson Anders, Taskinen Marja-Riitta, Burgess Stephen, Packard Chris J, Borén Jan
Abstract excerpt
BACKGROUND: Triglyceride-rich lipoproteins and remnants (TRL/remnants) have a causal, but not yet quantified, relationship with coronary heart disease (CHD): myocardial infarction plus revascularization. OBJECTIVES: The authors sought to estimate TRL/remnant per-particle atherogenicity, investigate causal relationships with inflammation, and determine whether differences in the atherogenicity of TRL/remnants and...
Topics
- Humans
- Triglycerides
- Polymorphism, Single Nucleotide
- Inflammation
- Male
- Risk Assessment
- Female
- Middle Aged
- Atherosclerosis
- Lipoproteins
- Cholesterol
- Coronary Disease
- Genome-Wide Association Study