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Article

Inflammation may explain part of atherosclerotic cardiovascular disease risk conferred by elevated remnant lipoproteins: a cohort and Mendelian randomization study.

Atherosclerosis - 1 Jun 2026

Wadström Benjamin N, Wulff Anders B, Pedersen Kasper M, Nordestgaard Børge G

Abstract excerpt

BACKGROUND AND AIMS: Elevated remnant lipoproteins are a causal risk factor for atherosclerotic cardiovascular disease. We tested the hypothesis that low-grade inflammation can explain part of the increased risk of peripheral artery disease (PAD) and myocardial infarction conferred by elevated remnant lipoproteins; we also explored the causal effect of genetically elevated remnant cholesterol on inflammatory...

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PMID: 42096871
DOI: 10.1016/j.atherosclerosis.2026.120772

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TNF

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