Article
The joint effects of ADH1B variants and childhood adversity on alcohol related phenotypes in African-American and European-American women and men.
Alcoholism, clinical and experimental research - 1 Dec 2014
Sartor Carolyn E, Wang Zuoheng, Xu Ke, Kranzler Henry R, Gelernter Joel
Abstract excerpt
BACKGROUND: The ADH1B gene has consistently been implicated in problem drinking, but rarely incorporated into gene by environment investigations of alcohol phenotypes. This study examined the joint effects of variation in ADH1B and childhood adversity-a well-documented risk factor for alcohol problems and moderator of genetic liability to psychiatric outcomes-on maximum drinks consumed in a 24-hour period...
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