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Article

Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers.

Addiction biology - 1 Jan 2015

Meyers Jacquelyn L, Shmulewitz Dvora, Wall Melanie M, Keyes Katherine M, Aharonovich Efrat, Spivak Baruch, Weizman Abraham, Frisch Amos, Edenberg Howard J, Gelernter Joel, Grant Bridget F, Hasin Deborah

Abstract excerpt

Childhood adversity and genetic variant ADH1B-rs1229984 have each been shown to influence heavy alcohol consumption and disorders. However, little is known about how these factors jointly influence these outcomes. We assessed the main and additive interactive effects of childhood adversity (abuse, neglect and parental divorce) and the ADH1B-rs1229984 on the quantitative phenotypes 'maximum drinks in a day'...

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Identifiers

PMID: 24164917
DOI: 10.1111/adb.12102
PMCID: PMC3999313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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