An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction.

doi:10.1111/acer.12524

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Article

An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction.

Alcoholism, clinical and experimental research - 1 Oct 2014

Olfson Emily, Edenberg Howard J, Nurnberger John, Agrawal Arpana, Bucholz Kathleen K, Almasy Laura A, Chorlian David, Dick Danielle M, Hesselbrock Victor M, Kramer John R, Kuperman Samuel, Porjesz Bernice, Schuckit Marc A, Tischfield Jay A, Wang Jen-Chyong, Wetherill Leah, Foroud Tatiana M, Rice John, Goate Alison, Bierut Laura J

Abstract excerpt

BACKGROUND: Adolescent drinking is an important public health concern, one that is influenced by both genetic and environmental factors. The functional variant rs1229984 in alcohol dehydrogenase 1B (ADH1B) has been associated at a genome-wide level with alcohol use disorders in diverse adult populations. However, few data are available regarding whether this variant influences early drinking behaviors and whether...

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PMID: 25257461
DOI: 10.1111/acer.12524
PMCID: PMC4256939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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