Association of polymorphism in microRNA 604 with susceptibility to persistent hepatitis B virus infection and development of hepatocellular carcinoma.

doi:10.3346/jkms.2014.29.11.1523

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Article

Association of polymorphism in microRNA 604 with susceptibility to persistent hepatitis B virus infection and development of hepatocellular carcinoma.

Journal of Korean medical science - 1 Nov 2014

Cheong Jae Youn, Shin Hyoung Doo, Cho Sung Won, Kim Yoon Jun

Abstract excerpt

MicroRNA polymorphisms may be associated with carcinogenesis or immunopathogenesis of infection. We evaluated whether the mircoRNA-604 (miR-604) polymorphism can affect the persistence of hepatitis B virus (HBV) infection, and the development to hepatocellular carcinoma (HCC) in patients with chronic HBV infection. A total of 1,439 subjects, who have either past or present HBV infection, were enrolled and divided...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Carcinoma, Hepatocellular
Case-Control Studies
Demography
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis B Antibodies

Hepatitis B Surface Antigens

Hepatitis B e Antigens

Hepatitis B virus

Hepatitis B, Chronic

Humans

Liver Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25408584
DOI: 10.3346/jkms.2014.29.11.1523
PMCID: PMC4234920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-25408584-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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