Article
A meta-analysis of the relation of polymorphism at sites -1082 and -592 of the IL-10 gene promoter with susceptibility and clearance to persistent hepatitis B virus infection in the Chinese population.
Infection - 1 Feb 2011
Zhang T-C, Pan F-M, Zhang L-Z, Gao Y-F, Zhang Z-H, Gao J, Ge R, Mei Y, Shen B-B, Duan Z-H, Li X
Abstract excerpt
BACKGROUND: Up to now, many publications about the Chinese population have evaluated the correlation between interleukin-10 (IL-10) -1082 and -592 polymorphisms and persistent hepatitis B virus (HBV) infection. However, the results remain inconclusive. In order to resolve this conflict, a meta-analysis was performed. METHODS: Seven studies were included and dichotomous data are presented as the odds ratio (OR)...
Topics
- China
- Genetic Predisposition to Disease
- Hepatitis B
- Humans
- Immunity, Innate
- Interleukin-10
- Polymorphism, Genetic
- Promoter Regions, Genetic