Article
Association of a microRNA-323b polymorphism with the persistence of hepatitis B virus infection by the enhancement of viral replication.
Journal of viral hepatitis - 1 Dec 2014
Yu S J, Kim J-W, Lee J-H, Yoon J-H, Lee H-S, Cheong J Y, Cho S W, Shin H D, Kim Y J
Abstract excerpt
Recent studies have shown that some mammalian microRNAs (miRNAs) play a role in antiviral defence. However, little is known about the role of miRNA-323b in hepatitis B virus (HBV)-host interaction. We explored whether single nucleotide polymorphism (SNP) of miRNA-323b affects HBV replication in a Korean HBV cohort. Genotyping was performed in a total of 1439 subjects composed of 404 spontaneously recovered (SR)...
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