Article
Bone morphogenic protein-4.
The international journal of biochemistry & cell biology - 1 Dec 1996
Leong L M, Brickell P M
Abstract excerpt
Bone morphogenic protein-4 (BMP-4) is one of nine structurally related BMPs belonging to the transforming growth factor-beta (TGF-beta) superfamily of secreted proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. Although discovered because it stimulates bone formation in adult mammals, BMP-4 has important roles as a signalling molecule in...
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