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Article

A versatile omnibus test for detecting mean and variance heterogeneity.

Genetic epidemiology - 1 Jan 2014

Cao Ying, Wei Peng, Bailey Matthew, Kauwe John S K, Maxwell Taylor J

Abstract excerpt

Recent research has revealed loci that display variance heterogeneity through various means such as biological disruption, linkage disequilibrium (LD), gene-by-gene (G × G), or gene-by-environment interaction. We propose a versatile likelihood ratio test that allows joint testing for mean and variance heterogeneity (LRT(MV)) or either effect alone (LRT(M) or LRT(V)) in the presence of covariates. Using extensive...

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Identifiers

PMID: 24482837
DOI: 10.1002/gepi.21778
PMCID: PMC4019404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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