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Article

Potential Roles of BMP9 in Liver Fibrosis

11 Nov 2014

Abstract excerpt

Liver fibrosis is a common phenomenon that is associated with several pathologies and is characterized by excessive extracellular matrix deposition that leads to progressive liver dysfunction. Bone morphogenetic protein 9 (BMP9) is the most recently discovered member of the BMP family. BMP9 bound with high affinity to activin receptor-like kinase 1 (ALK1) and endoglin in non-parenchymal liver cells. In addition,...

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PMID: 25393508
DOI: 10.3390/ijms151120656

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