Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice

13 Sept 2019

Abstract excerpt

The aim of the present work was to address the role of BMP9 in different genetic backgrounds (C57BL/6, BALB/c, and 129/Ola) of mice deleted for Bmp9. We found that Bmp9 deletion led to premature mortality only in the 129/Ola strain. We have previously shown that Bmp9 deletion led to liver sinusoidal endothelial cells (LSEC) capillarization and liver fibrosis in the 129/Ola background. Here, we showed that this is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective Tissue Growth Factor Research
Share to Liver physiology and pathology
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31540222
DOI: 10.3390/cells8091079

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 MicePMID 31540222Read ↗

BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations.Semantic proximity Read ↗

New insights into BMP9 signaling in organ fibrosisSemantic proximity Read ↗

Potential Roles of BMP9 in Liver FibrosisSemantic proximity Read ↗

Molecular mechanisms of liver and bile duct developmentSemantic proximity Read ↗

Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolismSemantic proximity Read ↗

Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formationSemantic proximity Read ↗

Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice.Semantic proximity Read ↗

BMP Signalling at the Crossroad of Liver Fibrosis and RegenerationSemantic proximity Read ↗

Hepatic stellate cells control liver zonation, size and functions via R-spondin 3Semantic proximity Read ↗

Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway ActivationSemantic proximity Read ↗

GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice.Semantic proximity Read ↗

Liver Sinusoidal Endothelium: A Microenvironment-Dependent Differentiation Program in Rat Including the Novel Junctional Protein Liver Endothelial Differentiation-Associated Protein-1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.