Article
Combined associations of genetic and environmental risk factors: implications for prevention of breast cancer.
Journal of the National Cancer Institute - 1 Nov 2014
Garcia-Closas Montserrat, Gunsoy Necdet Burak, Chatterjee Nilanjan
Abstract excerpt
Genome-wide association studies (GWAS) have identified hundreds of genetic susceptibility loci for cancers and other complex diseases. However, the public health and clinical relevance of these discoveries is unclear. Evaluating the combined associations of genetic and environmental risk factors, particularly those that can be modified, will be critical in assessing the utility of genetic information for risk...
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