Article
Common polymorphisms in the XPD and hOGG1 genes are not associated with the risk of colorectal cancer in a Polish population.
The Tohoku journal of experimental medicine - 1 Jul 2009
Sliwinski Tomasz, Krupa Renata, Wisniewska-Jarosinska Maria, Pawlowska Elzbieta, Lech Justyna, Chojnacki Jan, Blasiak Janusz
Abstract excerpt
Mutations in the DNA repair genes may contribute to the increased risk of cancer, including colorectal cancer. Xeroderma pigmentosum group D (XPD) protein and human homolog of the 8-oxoguanine glycosylase 1 (hOGG1) are involved in nucleotide excision repair and base excision repair, respectively. The XPD and the hOGG1 genes are highly polymorphic, and some of their polymorphisms are associated with several types...
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