Article
The association between XPG polymorphisms and cancer susceptibility: Evidence from observational studies.
Medicine - 1 Aug 2017
Han Cuihong, Huang Xiaoyi, Hua Ruixi, Song Shujie, Lyu Lihua, Ta Na, Zhu Jinhong, Zhang Peixi
Abstract excerpt
BACKGROUND: Exposure to environmental carcinogens can cause damages to DNA. If not properly repaired, the DNA damages may increase the risk of carcinogenesis. Xeroderma pigmentosum group G (XPG) gene is an essential gene in the nucleotide excision repair (NER) pathway. The association between XPG polymorphisms and cancer susceptibility has been the focus of attention in the molecular epidemiology of cancer....
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