Article
XPG gene polymorphisms and cancer susceptibility: evidence from 47 studies.
Oncotarget - 6 Jun 2017
Huang Jiawen, Liu Xiaoqi, Tang Ling-Ling, Long Jian-Ting, Zhu Jinhong, Hua Rui-Xi, Li Jufeng
Abstract excerpt
Xeroderma pigmentosum group G (XPG) is a single-strand-specific DNA endonuclease that functions in the nucleotide excision repair pathway. Genetic variations in XPG gene can alter the DNA repair capacity of this enzyme. We evaluated the associations between six single nucleotide polymorphisms (SNPs) in XPG (rs1047768 T>C, rs2296147 T>C, rs2227869 G>C, rs2094258 C>T, rs751402 C>T, and G>A) and cancer...