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Article

Double-stranded DNA-dependent ATPase Irc3p is directly involved in mitochondrial genome maintenance.

Nucleic acids research - 1 Dec 2014

Sedman Tiina, Gaidutšik Ilja, Villemson Karin, Hou YingJian, Sedman Juhan

Abstract excerpt

Nucleic acid-dependent ATPases are involved in nearly all aspects of DNA and RNA metabolism. Previous studies have described a number of mitochondrial helicases. However, double-stranded DNA-dependent ATPases, including translocases or enzymes remodeling DNA-protein complexes, have not been identified in mitochondria of the yeast Saccharomyces cerevisae. Here, we demonstrate that Irc3p is a mitochondrial...

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Identifiers

PMID: 25389272
DOI: 10.1093/nar/gku1148
PMCID: PMC4245962

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Source receipt: pubmed, retrieved 7 Sept 2026.

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