Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation.

The Journal of biological chemistry - 4 Nov 2011

Guo Xuning Emily, Chen Chi-Fen, Wang Dennis Ding-Hwa, Modrek Aram Sandaldjian, Phan Vy Hoai, Lee Wen-Hwa, Chen Phang-Lang

Abstract excerpt

Yeast SUV3 is a nuclear encoded mitochondrial RNA helicase that complexes with an exoribonuclease, DSS1, to function as an RNA degradosome. Inactivation of SUV3 leads to mitochondrial dysfunctions, such as respiratory deficiency; accumulation of aberrant RNA species, including excised group I introns; and loss of mitochondrial DNA (mtDNA). Although intron toxicity has long been speculated to be the major reason...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphate
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DEAD-box RNA Helicases

Share to Genome, Mitochondrial

Share to Membrane Potentials

Share to RNA Helicases

Share to RNA Stability

Source

Open in PubMed Open full text

Identifiers

PMID: 21911497
DOI: 10.1074/jbc.M111.257956
PMCID: PMC3207411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation.PMID 21911497Read ↗

Splicing of yeast aI5beta group I intron requires SUV3 to recycle MRS1 via mitochondrial degradosome-promoted decay of excised intron ribonucleoprotein (RNP).Semantic proximity Read ↗

Balance between transcription and RNA degradation is vital for Saccharomyces cerevisiae mitochondria: reduced transcription rescues the phenotype of deficient RNA degradation.Semantic proximity Read ↗

The SUV3 gene from Saccharomyces douglasii is a functional equivalent of its Saccharomyces cerevisiae orthologue and is essential for respiratory growth.Semantic proximity Read ↗

Double-stranded DNA-dependent ATPase Irc3p is directly involved in mitochondrial genome maintenance.Semantic proximity Read ↗

The nuclear SUV3-1 mutation affects a variety of post-transcriptional processes in yeast mitochondria.Semantic proximity Read ↗

Biallelic mutations in SUPV3L1 cause an inherited neurodevelopmental disorder with variable leukodystrophy due to aberrant mitochondrial double stranded RNA processingSemantic proximity Read ↗

A viable hypomorphic allele of the essential IMP3 gene reveals novel protein functions in Saccharomyces cerevisiae.Semantic proximity Read ↗

Pervasive transcription of the mitochondrial genome in Candida albicans is revealed in mutants lacking the mtEXO RNase complex.Semantic proximity Read ↗

Mitochondrial RNA processing defect caused by a SUPV3L1 mutation in two siblings with a novel neurodegenerative syndrome.Semantic proximity Read ↗

A novel mitochondrial DEAD box protein (Mrh4) required for maintenance of mtDNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

A single subunit, Dis3, is essentially responsible for yeast exosome core activity.Semantic proximity Read ↗

Mitochondrial genome maintenance: roles for nuclear nonhomologous end-joining proteins in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.